ABSTRACT
In this issue of Kidney International, the initial experience regarding the immunogenicity of prior coronavirus disease 2019 (COVID-19) infection and the response to the COVID-19 vaccines among patients on maintenance dialysis and kidney transplant recipients is summarized. Preliminary data suggest that there is durability of immune response after COVID-19 infection. Although immune response to the first dose of vaccine is less in infection-naïve patients than healthy individuals in both groups, after the second vaccine dose a significant portion of patients receiving maintenance dialysis develop robust antibody titers, whereas kidney transplant recipients show a less-strong immune response.
Subject(s)
COVID-19 Vaccines/administration & dosage , COVID-19 Vaccines/immunology , COVID-19/prevention & control , Kidney Transplantation , Renal Dialysis , Aged , COVID-19/complications , COVID-19 Vaccines/adverse effects , Female , Humans , Immunity , Male , Middle Aged , Outcome and Process Assessment, Health Care , Pandemics/prevention & control , Renal Replacement Therapy , SARS-CoV-2 , VaccinationSubject(s)
COVID-19 Vaccines/therapeutic use , COVID-19/prevention & control , Health Services Needs and Demand , Kidney Failure, Chronic/therapy , Needs Assessment , Renal Dialysis , Vaccination , Aged , Aged, 80 and over , COVID-19/diagnosis , COVID-19/mortality , Female , Health Services Accessibility , Healthcare Disparities , Humans , Kidney Failure, Chronic/diagnosis , Kidney Failure, Chronic/mortality , Male , Middle Aged , Policy Making , Renal Dialysis/adverse effects , Renal Dialysis/mortality , Risk Assessment , Risk Factors , Vulnerable PopulationsSubject(s)
Betacoronavirus , Coronavirus Infections , Pandemics , Pneumonia, Viral , Renal Insufficiency, Chronic , COVID-19 , Humans , Resource Allocation , SARS-CoV-2Subject(s)
Betacoronavirus/immunology , Coronavirus Infections/prevention & control , Infection Control/standards , Kidney Failure, Chronic/therapy , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , Renal Dialysis/standards , Betacoronavirus/isolation & purification , COVID-19 , Coronavirus Infections/epidemiology , Coronavirus Infections/virology , Cross-Cultural Comparison , Evidence-Based Medicine/standards , Humans , Kidney Failure, Chronic/immunology , Patient Education as Topic/standards , Pneumonia, Viral/epidemiology , Pneumonia, Viral/virology , Practice Guidelines as Topic , SARS-CoV-2Subject(s)
Betacoronavirus , Coronavirus Infections/prevention & control , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , Renal Insufficiency, Chronic/therapy , COVID-19 , Coronavirus Infections/transmission , Health Personnel/education , Humans , Patient Selection , Pneumonia, Viral/transmission , Renal Dialysis , Risk Factors , SARS-CoV-2Subject(s)
Betacoronavirus , Coronavirus Infections/prevention & control , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , Renal Dialysis , COVID-19 , Coronavirus Infections/transmission , Health Planning , Humans , Inpatients , Medical Staff , Pneumonia, Viral/transmission , Renal Dialysis/methods , SARS-CoV-2Subject(s)
Betacoronavirus , Coronavirus Infections/complications , Disease Transmission, Infectious/prevention & control , Kidney Failure, Chronic/therapy , Pandemics , Pneumonia, Viral/complications , Renal Dialysis/methods , COVID-19 , Coronavirus Infections/epidemiology , Humans , Kidney Failure, Chronic/complications , Outpatients , Pneumonia, Viral/epidemiology , Risk Factors , SARS-CoV-2 , SafetyABSTRACT
The clinical presentation and mortality rate in maintenance hemodialysis (MHD) patients with COVID-19 are not well established. Recent data from Italy and Spain suggest that these patients present with wide range of symptoms, with a significant portion being asymptomatic. There is prolonged positivity of pharyngeal swabs in MHD patients. The mortality rates are very high, reaching almost 30%. These data highlight the importance of diligent oversight and care of MHD patients during COVID-19 pandemic.